Mission:
The mission of the Joint Center for Innovative Membrane Protein Technologies (JCIMPT) is to develop and disseminate methods and technologies for structure-grade production of integral membrane proteins. Miniaturization and automation are major components in the systematic investigation of membrane proteins and in the development of novel genetically engineered expression systems and sample preparation technologies. The structure of the JCIMPT includes three primary projects: Membrane Protein Expression; Membrane Protein Stabilization;and Membrane Protein Biophysical Analysis.
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| | Roth CB, Hanson MA, Stevens RC | J Mol Biol | 376 | 1305-1319 | 2008 | PMID:18222471 | | | Alexandrov AI, Mileni M, Chien EY, Hanson MA, Stevens RC | Structure | 16 | 351-359 | 2008 | PMID:18334210 | | | M.A. Hanson, V. Cherezov, C.B. Roth, M.T. Griffith, V.-P. Jaakola, E.Y.T. Chien, J. Velasquez, P. Kuhn, R.C. Stevens | Structure | 16 | 897-905 | 2008 | DOI:10.1016/j.str.2008.05.001 | | | Q. Zhang, R. Horst, M. Geralt, X. Ma, W.X. Hong, M.G. Finn, R.C. Stevens, K. Wüthrich | J. Am. Chem. Soc. | 130 | 7357-7363 | 2008 | DOI:10.1021/ja077863d | | | J.D. Ng, R.C. Stevens, P. Kuhn | Methods Mol. Biol. | 426 | 363-376 | 2008 | DOI:10.1007/978-1-60327-058-8 | | | J.D. Ng, P.J. Clark, R.C. Stevens, P. Kuhn | Acta Crystallogr | D 64 | 189-197 | 2008 | | | | Zhang Q, Ma X, Ward A, Hong WX, Jaakola VP, Stevens RC, Finn MG, Chang G | Angew Chem Int Ed Engl | 46 | 7023-7025 | 2007 | PMID:17691085 | | | Ward A, Reyes CL, Yu J, Roth CB, Chang G | Proc Natl Acad Sci U S A | 104 | 19005-19010 | 2007 | PMID:18024585 | | | Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, et al. | Science | 318 | 1266-1273 | 2007 | PMID:17962519 | | | Hanson MA, Brooun A, Baker KA, Jaakola VP, Roth C, Chien EY, Alexandrov A, Velasquez J, Davis L, Griffith M, et al. | Protein Expr Purif | 56 | 85-92 | 2007 | PMID:17723307 | | | Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, et al. | Science | 318 | 1258-1265. | 2007 | PMID:17962520 | | | Chen YJ, Pornillos O, Lieu S, Ma C, Chen AP, Chang G | Proc Natl Acad Sci U S A | 104 | 18999-19004 | 2007 | PMID:18024586 |
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