| 80. | C. Wang, Y. Jiang, J. Ma, H. Wu, D. Wacker, V. Katritch, G. W. Han, W. Liu, X. P. Huang, E. Vardy, J. D. McCorvy, X. Gao, E. X. Zhou, K. Melcher, C. Zhang, F. Bai, H. Yang, L. Yang, H. Jiang, B. L. Roth, V. Cherezov, R. C. Stevens and H. E. Xu
(2013)
Structural basis for molecular recognition at serotonin receptors
Science
online 21 Mar 2013:
|
| 79. |
D. Wacker, C. Wang, V. Katritch, G. W. Han, X. P. Huang, E. Vardy, J. D. McCorvy, Y. Jiang, M. Chu, F. Y. Siu, W. Liu, H. E. Xu, V. Cherezov, B. L. Roth and R. C. Stevens
(2013)
Structural features for functional selectivity at serotonin receptors
Science
online 21 Mar 2013:
|
| 78. |
R. C. Stevens, V. Cherezov, V. Katritch, R. Abagyan, P. Kuhn, H. Rosen and K. Wuthrich
(2013)
The GPCR Network: a large-scale collaboration to determine human GPCR structure and function
Nat Rev Drug Discov
12:
25-34 ;
|
| 77. |
S. C. Lee, B. C. Bennett, W. X. Hong, Y. Fu, K. A. Baker, J. Marcoux, C. V. Robinson, A. B. Ward, J. R. Halpert, R. C. Stevens, C. D. Stout, M. J. Yeager and Q. Zhang
(2013)
Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins
Proc Natl Acad Sci U S A
|
| 76. |
V. Katritch, V. Cherezov and R. C. Stevens
(2013)
Structure-Function of the G Protein-Coupled Receptor Superfamily
Annu Rev Pharmacol Toxicol
53:
531-556 ;
|
| 75. |
R. Horst, P. Stanczak, R. C. Stevens and K. Wuthrich
(2013)
beta(2) -Adrenergic Receptor Solutions for Structural Biology Analyzed with Microscale NMR Diffusion Measurements
Angew Chem Int Ed Engl
52:
331-335 ;
|
| 74. |
Y. Xu, A. Moeller, S. Y. Jun, M. Le, B. Y. Yoon, J. S. Kim, K. Lee and N. C. Ha
(2012)
Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria
J Biol Chem
287:
11740-50 ;
|
| 73. |
H. Wu, D. Wacker, M. Mileni, V. Katritch, G. W. Han, E. Vardy, W. Liu, A. A. Thompson, X. P. Huang, F. I. Carroll, S. W. Mascarella, R. B. Westkaemper, P. D. Mosier, B. L. Roth, V. Cherezov and R. C. Stevens
(2012)
Structure of the human kappa-opioid receptor in complex with JDTic
Nature
485:
327-332 ;
|
| 72. |
P. R. Wilderman, S. C. Gay, H. H. Jang, Q. Zhang, C. D. Stout and J. R. Halpert
(2012)
Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme
FEBS J
279:
1607-20 ;
|
| 71. |
J. F. White, N. Noinaj, Y. Shibata, J. Love, B. Kloss, F. Xu, J. Gvozdenovic-Jeremic, P. Shah, J. Shiloach, C. G. Tate and R. Grisshammer
(2012)
Structure of the agonist-bound neurotensin receptor
Nature
490:
508-13 ;
|
| 70. |
A. A. Thompson, W. Liu, E. Chun, V. Katritch, H. Wu, E. Vardy, X. P. Huang, C. Trapella, R. Guerrini, G. Calo, B. L. Roth, V. Cherezov and R. C. Stevens
(2012)
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic
Nature
485:
395-9 ;
|
| 69. |
H. Tao, Y. Fu, A. A. Thompson, S. C. Lee, N. Mahoney, R. C. Stevens and Q. Zhang
(2012)
Synthesis and Properties of Dodecyl Trehaloside Detergents for Membrane Protein Studies
Langmuir
28:
11173-81. ;
|
| 68. |
P. Stanczak, Q. Zhang, R. Horst, P. Serrano and K. Wuthrich
(2012)
Micro-coil NMR to monitor optimization of the reconstitution conditions for the integral membrane protein OmpW in detergent micelles
J Biomol NMR
54:
129-133 ;
|
| 67. |
J. S. Santos, G. A. Asmar-Rovira, G. W. Han, W. Liu, R. Syeda, V. Cherezov, K. A. Baker, R. C. Stevens and M. Montal
(2012)
Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes
J Biol Chem
287:
43063-70 ;
|
| 66. |
A. Moeller, C. Zhao, M. G. Fried, E. M. Wilson-Kubalek, B. Carragher and S. W. Whiteheart
(2012)
Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly
J Struct Biol
177:
335-43 ;
|
| 65. |
A. Moeller, R. N. Kirchdoerfer, C. S. Potter, B. Carragher and I. A. Wilson
(2012)
Organization of the Influenza Virus Replication Machinery
Science
|
| 64. |
W. Liu, E. Chun, A. A. Thompson, P. Chubukov, F. Xu, V. Katritch, G. W. Han, C. B. Roth, L. H. Heitman, I. J. AP, V. Cherezov and R. C. Stevens
(2012)
Structural basis for allosteric regulation of GPCRs by sodium ions
Science
337:
232-6 ;
|
| 63. |
J. J. Liu, R. Horst, V. Katritch, R. C. Stevens and K. Wuthrich
(2012)
Biased signaling pathways in beta2-adrenergic receptor characterized by 19F-NMR
Science
335:
1106-10 ;
|
| 62. |
X. Jiang, L. Guan, Y. Zhou, W. X. Hong, Q. Zhang and H. R. Kaback
(2012)
Evidence for an intermediate conformational state of LacY
Proc Natl Acad Sci U S A
109:
E698-704 ;
|
| 61. |
R. Horst, P. Stanczak, P. Serrano and K. Wuthrich
(2012)
Translational Diffusion Measurements by Microcoil NMR in Aqueous Solutions of the Fos-10 Detergent-Solubilized Membrane Protein OmpX
J Phys Chem B
116:
6775-80 ;
|
| 60. |
M. A. Hanson, C. B. Roth, E. Jo, M. T. Griffith, F. L. Scott, G. Reinhart, H. Desale, B. Clemons, S. M. Cahalan, S. C. Schuerer, M. G. Sanna, G. W. Han, P. Kuhn, H. Rosen and R. C. Stevens
(2012)
Crystal structure of a lipid G protein-coupled receptor
Science
335:
851-5 ;
|
| 59. |
J. W. Fairman, N. Dautin, D. Wojtowicz, W. Liu, N. Noinaj, T. J. Barnard, E. Udho, T. M. Przytycka, V. Cherezov and S. K. Buchanan
(2012)
Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis
Structure
20:
1233-43 ;
|
| 58. |
E. Chun, A. A. Thompson, W. Liu, C. B. Roth, M. T. Griffith, V. Katritch, J. Kunken, F. Xu, V. Cherezov, M. A. Hanson and R. C. Stevens
(2012)
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors
Structure
20:
967-76 ;
|
| 57. |
Author: E. E. Abola, V. Cherezov and R. C. Stevens
Year: 2012
Title: X-ray crystallography: crystallization
Secondary Author: E. H. Egelman
Secondary Title: Comprehensive Biophysics
Place Published: Oxford
Publisher: Academic Press
Volume: 1
Pages: 34-63
Tertiary Author: H. J. Dyson
Tertiary Title: Biophysical Techniques for Structural Characterization of Macromolecules
Short Title: X-ray crystallography: crystallization
|
| 56. |
Q. Zhang, H. Tao and W. X. Hong
(2011)
New amphiphiles for membrane protein structural biology
Methods
55:
318-23 ;
|
| 55. |
Y. Xu, S. Song, A. Moeller, N. Kim, S. Piao, S. H. Sim, M. Kang, W. Yu, H. S. Cho, I. Chang, K. Lee and N. C. Ha
(2011)
Functional implications of an intermeshing cogwheel-like interaction between TolC and MacA in the action of macrolide-specific efflux pump MacAB-TolC
J Biol Chem
286:
13541-9 ;
|
| 54. |
Y. Xu, M. Lee, A. Moeller, S. Song, B. Y. Yoon, H. M. Kim, S. Y. Jun, K. Lee and N. C. Ha
(2011)
Funnel-like Hexameric Assembly of the Periplasmic Adapter Protein in the Tripartite Multidrug Efflux Pump in Gram-negative Bacteria
J Biol Chem
286:
17910-20 ;
|
| 53. |
F. Xu, H. Wu, V. Katritch, G. W. Han, K. A. Jacobson, Z. G. Gao, V. Cherezov and R. C. Stevens
(2011)
Structure of an agonist-bound human A2A adenosine receptor
Science
332:
322-7 ;
|
| 52. |
F. Xu, W. Liu, M. A. Hanson, R. C. Stevens and V. Cherezov
(2011)
Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases
Cryst Growth Des
11:
1193-1201 ;
|
| 51. |
T. Tiefenbrunn, W. Liu, Y. Chen, V. Katritch, C. D. Stout, J. A. Fee and V. Cherezov
(2011)
High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment
PLoS One
6:
e22348 ;
|
| 50. |
A. A. Thompson, J. J. Liu, E. Chun, D. Wacker, H. Wu, V. Cherezov and R. C. Stevens
(2011)
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles
Methods
55:
310-7 ;
|
| 49. |
T. Shimamura, M. Shiroishi, S. Weyand, H. Tsujimoto, G. Winter, V. Katritch, R. Abagyan, V. Cherezov, W. Liu, G. W. Han, T. Kobayashi, R. C. Stevens and S. Iwata
(2011)
Structure of the human histamine H(1) receptor complex with doxepin
Nature
475:
65-70 ;
|
| 48. |
M. B. Shah, J. Pascual, Q. Zhang, C. D. Stout and J. R. Halpert
(2011)
Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains
Mol Pharmacol
80:
1047-55 ;
|
| 47. |
M. T. Miller, M. Mileni, D. Comoletti, R. C. Stevens, M. Harel and P. Taylor
(2011)
The Crystal Structure of the alpha-Neurexin-1 Extracellular Region Reveals a Hinge Point for Mediating Synaptic Adhesion and Function
Structure
19:
767-78 ;
|
| 46. |
A. C. Milazzo, A. Cheng, A. Moeller, D. Lyumkis, E. Jacovetty, J. Polukas, M. H. Ellisman, N. H. Xuong, B. Carragher and C. S. Potter
(2011)
Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy
J Struct Biol
176:
404-8 ;
|
| 45. |
W. Liu and V. Cherezov
(2011)
Crystallization of membrane proteins in lipidic mesophases
J Vis Exp
|
| 44. |
J. S. Joseph, W. Liu, J. Kunken, T. M. Weiss, H. Tsuruta and V. Cherezov
(2011)
Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering
Methods
55:
342-9 ;
|
| 43. |
R. Horst, A. L. Horwich and K. Wuthrich
(2011)
Translational diffusion of macromolecular assemblies measured using transverse-relaxation-optimized pulsed field gradient NMR
J Am Chem Soc
133:
16354-7 ;
|
| 42. |
L. M. Haupert and G. J. Simpson
(2011)
Screening of protein crystallization trials by second order nonlinear optical imaging of chiral crystals (SONICC)
Methods
55:
379-86 ;
|
| 41. |
S. C. Gay, H. Zhang, P. R. Wilderman, A. G. Roberts, T. Liu, S. Li, H. L. Lin, Q. Zhang, V. L. Woods, Jr., C. D. Stout, P. F. Hollenberg and J. R. Halpert
(2011)
Structural analysis of mammalian cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene: insight into partial enzymatic activity
Biochemistry
50:
4903-11 ;
|
| 40. |
L. S. Fisher, A. Ward, R. A. Milligan, N. Unwin, C. S. Potter and B. Carragher
(2011)
A helical processing pipeline for EM structure determination of membrane proteins
Methods
55:
350-62 ;
|
| 39. |
V. Cherezov
(2011)
Lipidic cubic phase technologies for membrane protein structural studies
Curr Opin Struct Biol
21:
559-66 ;
|
| 38. |
M. M. Baksh, A. K. Kussrow, M. Mileni, M. G. Finn and D. J. Bornhop
(2011)
Label-free quantification of membrane-ligand interactions using backscattering interferometry
Nat Biotechnol
29:
357-60 ;
|
| 37. |
X. Zhang, E. Y. Chien, M. J. Chalmers, B. D. Pascal, J. Gatchalian, R. C. Stevens and P. R. Griffin
(2010)
Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange
Anal Chem
82:
1100-8 ;
|
| 36. |
B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D. J. Hamel, P. Kuhn, T. M. Handel, V. Cherezov and R. C. Stevens
(2010)
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists
Science
330:
1066-71 ;
|
| 35. |
D. Wacker, G. Fenalti, M. A. Brown, V. Katritch, R. Abagyan, V. Cherezov and R. C. Stevens
(2010)
Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography
J Am Chem Soc
132:
11443-5 ;
|
| 34. |
T. A. Nguyen, S. S. Lieu and G. Chang
(2010)
An Escherichia coli-based cell-free system for large-scale production of functional mammalian membrane proteins suitable for X-ray crystallography
J Mol Microbiol Biotechnol
18:
85-91 ;
|
| 33. |
M. Michino, J. Chen, R. C. Stevens and C. L. Brooks, 3rd
(2010)
FoldGPCR: structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A
Proteins
78:
2189-201 ;
|
| 32. |
W. Liu, M. A. Hanson, R. C. Stevens and V. Cherezov
(2010)
LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment
Biophys J
98:
1539-48 ;
|
| 31. |
D. J. Kissick, E. J. Gualtieri, G. J. Simpson and V. Cherezov
(2010)
Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases
Anal Chem
82:
491-7 ;
|
| 30. |
V. Katritch, V. P. Jaakola, J. R. Lane, J. Lin, A. P. Ijzerman, M. Yeager, I. Kufareva, R. C. Stevens and R. Abagyan
(2010)
Structure-Based Discovery of Novel Chemotypes for Adenosine A(2A) Receptor Antagonists
J Med Chem
53:
1799-1809 ;
|
| 29. |
V. P. Jaakola, J. R. Lane, J. Y. Lin, V. Katritch, A. P. Ijzerman and R. C. Stevens
(2010)
Identification and characterization of amino acid residues essential for human A2A adenosine receptor : ZM241385 binding and subtype selectivity
J Biol Chem
285:
13032-13044 ;
|
| 28. |
W. X. Hong, K. A. Baker, X. Ma, R. C. Stevens, M. Yeager and Q. Zhang
(2010)
Design, synthesis, and properties of branch-chained maltoside detergents for stabilization and crystallization of integral membrane proteins: human connexin 26
Langmuir
26:
8690-6 ;
|
| 27. |
X. He, P. Szewczyk, A. Karyakin, M. Evin, W. X. Hong, Q. Zhang and G. Chang
(2010)
Structure of a cation-bound multidrug and toxic compound extrusion transporter
Nature
467:
991-4 ;
|
| 26. |
S. C. Gay, M. B. Shah, J. C. Talakad, K. Maekawa, A. G. Roberts, P. R. Wilderman, L. Sun, J. Y. Yang, S. C. Huelga, W. X. Hong, Q. Zhang, C. D. Stout and J. R. Halpert
(2010)
Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution
Mol Pharmacol
77:
529-38 ;
|
| 25. |
S. C. Gay, A. G. Roberts, K. Maekawa, J. C. Talakad, W. X. Hong, Q. Zhang, C. D. Stout and J. R. Halpert
(2010)
Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel
Biochemistry
49:
8709-20 ;
|
| 24. |
Y. Fu, Y. Weng, W. X. Hong and Q. Zhang
(2010)
Efficient Synthesis of Unsaturated 1-Monoacyl Glycerols for in meso Crystallization of Membrane Proteins
Synlett
2011:
809-812 ;
|
| 23. |
E. Y. Chien, W. Liu, Q. Zhao, V. Katritch, G. W. Han, M. A. Hanson, L. Shi, A. H. Newman, J. A. Javitch, V. Cherezov and R. C. Stevens
(2010)
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist
Science
330:
1091-5 ;
|
| 22. |
P. Stanczak, R. Horst, P. Serrano and K. Wuthrich
(2009)
NMR characterization of membrane protein-detergent micelle solutions by use of microcoil equipment
J Am Chem Soc
131:
18450-6 ;
|
| 21. |
M. Michino, E. Abola, C. L. Brooks, 3rd, J. S. Dixon, J. Moult and R. C. Stevens
(2009)
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008
Nat Rev Drug Discov
8:
455-63 ;
|
| 20. |
V. Katritch, K. A. Reynolds, V. Cherezov, M. A. Hanson, C. B. Roth, M. Yeager and R. Abagyan
(2009)
Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes
J Mol Recognit
22:
307-18 ;
|
| 19. |
M. A. Hanson and R. C. Stevens
(2009)
Discovery of new GPCR biology: one receptor structure at a time
Structure
17:
8-14 ;
|
| 18. |
V. Cherezov, M. A. Hanson, M. T. Griffith, M. C. Hilgart, R. Sanishvili, V. Nagarajan, S. Stepanov, R. F. Fischetti, P. Kuhn and R. C. Stevens
(2009)
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam
J R Soc Interface
6 Suppl 5:
S587-97 ;
|
| 17. |
M. Caffrey and V. Cherezov
(2009)
Crystallizing membrane proteins using lipidic mesophases
Nat Protoc
4:
706-31 ;
|
| 16. |
S. G. Aller, J. Yu, A. Ward, Y. Weng, S. Chittaboina, R. Zhuo, P. M. Harrell, Y. T. Trinh, Q. Zhang, I. L. Urbatsch and G. Chang
(2009)
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding
Science
323:
1718-22 ;
|
| 15. |
Q. Zhang, R. Horst, M. Geralt, X. Ma, W. X. Hong, M. G. Finn, R. C. Stevens and K. Wuthrich
(2008)
Microscale NMR screening of new detergents for membrane protein structural biology
J Am Chem Soc
130:
7357-63 ;
|
| 14. |
C. B. Roth, M. A. Hanson and R. C. Stevens
(2008)
Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure
J Mol Biol
376:
1305-19 ;
|
| 13. |
J. D. Ng, R. C. Stevens and P. Kuhn
(2008)
Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomics
Methods Mol Biol
426:
363-76 ;
|
| 12. |
J. D. Ng, P. J. Clark, R. C. Stevens and P. Kuhn
(2008)
In situ X-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels
Acta Crystallogr D Biol Crystallogr
64:
189-97 ;
|
| 11. |
V. P. Jaakola, M. T. Griffith, M. A. Hanson, V. Cherezov, E. Y. Chien, J. R. Lane, A. P. Ijzerman and R. C. Stevens
(2008)
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
Science
|
| 10. |
M. A. Hanson, V. Cherezov, M. T. Griffith, C. B. Roth, V. P. Jaakola, E. Y. Chien, J. Velasquez, P. Kuhn and R. C. Stevens
(2008)
A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor
Structure
16:
897-905 ;
|
| 9. |
A. I. Alexandrov, M. Mileni, E. Y. Chien, M. A. Hanson and R. C. Stevens
(2008)
Microscale fluorescent thermal stability assay for membrane proteins
Structure
16:
351-9 ;
|
| 8. |
E. E. Abola and R. C. Stevens
(2008)
The importance of target selection strategies in structural biology
J. L. Sussman and I. Silman
Structural proteomics and its impact on the life sciences
Singapore
World Scientific Publishing Co.
1-28
|
| 7. |
Q. Zhang, X. Ma, A. Ward, W. X. Hong, V. P. Jaakola, R. C. Stevens, M. G. Finn and G. Chang
(2007)
Designing facial amphiphiles for the stabilization of integral membrane proteins
Angew Chem Int Ed Engl
46:
7023-5 ;
|
| 6. |
A. Ward, C. L. Reyes, J. Yu, C. B. Roth and G. Chang
(2007)
Flexibility in the ABC transporter MsbA: Alternating access with a twist
Proc Natl Acad Sci U S A
104:
19005-10 ;
|
| 5. |
D. M. Rosenbaum, V. Cherezov, M. A. Hanson, S. G. Rasmussen, F. S. Thian, T. S. Kobilka, H. J. Choi, X. J. Yao, W. I. Weis, R. C. Stevens and B. K. Kobilka
(2007)
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function
Science
318:
1266-73 ;
|
| 4. |
M. A. Hanson, A. Brooun, K. A. Baker, V. P. Jaakola, C. Roth, E. Y. Chien, A. Alexandrov, J. Velasquez, L. Davis, M. Griffith, K. Moy, B. K. Ganser-Pornillos, Y. Hua, P. Kuhn, S. Ellis, M. Yeager and R. C. Stevens
(2007)
Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression
Protein Expr Purif
56:
85-92 ;
|
| 3. |
V. Cherezov, D. M. Rosenbaum, M. A. Hanson, S. G. Rasmussen, F. S. Thian, T. S. Kobilka, H. J. Choi, P. Kuhn, W. I. Weis, B. K. Kobilka and R. C. Stevens
(2007)
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor
Science
318:
1258-65 ;
|
| 2. |
Y. J. Chen, O. Pornillos, S. Lieu, C. Ma, A. P. Chen and G. Chang
(2007)
X-ray structure of EmrE supports dual topology model
Proc Natl Acad Sci U S A
104:
18999-9004 ;
|