Structures

Num	PDB	Descriptor	Deposition Date	Authors	PDBSum	PubMed
54.	4FAA	Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus	5/21/2012	Li, Y., Chen, Y., Stout, C.D.	PDBSum	PubMed
53.	4FA7	Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus	5/21/2012	Li, Y., Chen, Y., Stout, C.D.	PDBSum	PubMed
52.	4F05	Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133F from Thermus thermophilus	5/13/2012	Li, Y., Chen, Y., Stout, C.D.	PDBSum	PubMed
51.	4EV3	Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W from Thermus thermophilus	4/25/2012	Li, Y., Chen, Y., Stout, C.D.	PDBSum	PubMed
50.	4ESL	Structure of Recombinant Cytochrome ba3 Oxidase mutant Y133W+T231F from Thermus thermophilus	4/23/2012	Li, Y., Chen, Y., Stout, C.D.	PDBSum	PubMed
49.	4EIY	Crystal structure of the chimeric protein of A2aAR-BRIL in complex with ZM241385 at 1.8A resolution	4/06/2012	Liu, W., Chun, E., Thompson, A.A., Chubukov, P., Xu, F., Katritch, V., Han, G.W., Heitman, L.H., Ijzerman, A.P., Cherezov, V., Stevens, R.C.	PDBSum	PubMed
48.	4EA3	Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.	3/22/2012	Thompson, A.A., Liu, W., Chun, E., Katritch, V., Wu, H., Vardy, E., Huang, X.P., Trapella, C., Guerrini, R., Calo, G., Roth, B.L., Cherezov, V., Stevens, R.C. Nature,2012;485:395-9.	PDBSum	PubMed
47.	4E1T	Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis.	3/07/2012	Fairman, J.W., Dautin, N., Wojtowicz, D., Liu, W., Noinaj, N., Barnard, T.J., Udho, E., A., Przytycka, T.M., Cherezov, V., Buchanan, S.K. Structure 2012	PDBSum	PubMed
46.	4E1S	Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic E. coli and Enteropathogenic Y. pseudotuberculosis.	3/07/2012	Fairman, J.W., Dautin, N., Wojtowicz, D., Liu, W., Noinaj, N., Barnard, T.J., Udho, E., A., Przytycka, T.M., Cherezov, V., Buchanan, S.K. Structure. 2012	PDBSum	PubMed
45.	4DJH	Structure of the human kappa-opioid receptor in complex with JDTic	2/01/2012	Wu H, Wacker D, Mileni M, Katritch V, Han GW, Vardy E, Liu W, Thompson AA, Huang XP, Carroll FI, Mascarella SW, Westkaemper RB, Mosier PD, Roth BL, Cherezov V, Stevens RC. Nature, 2012;485:327-32.	PDBSum	PubMed
44.	3V2W	Crystal structure of a lipid G protein-coupled receptor	12/12/2011	M.A. Hanson, C.B. Roth, E. Jo, M.T. Griffith, F.L. Scott, G. Reinhart, H. Desale, B. Clemons, S.M. Cahalan, S.C. Schuerer, M.G. Sanna, G.W. Han, P. Kuhn, H. Rosen, R.C. Stevens Science, 2012;335:851-5.	PDBSum	PubMed
43.	3V2Y	Crystal structure of a lipid G protein-coupled receptor	12/12/2011	M.A. Hanson, C.B. Roth, E. Jo, M.T. Griffith, F.L. Scott, G. Reinhart, H. Desale, B. Clemons, S.M. Cahalan, S.C. Schuerer, M.G. Sanna, G.W. Han, P. Kuhn, H. Rosen, R.C. Stevens Science, 2012;335:851-5.	PDBSum	PubMed
42.	3TK3	Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme.	8/25/2011	P.R. Wilderman, S.C. Gay, H.H. Jang, Q. Zhang, C.D. Stout, J.R. Halpert FEBS J., 2012;279:1607-20	PDBSum	PubMed
41.	3S8F	1.8 A structure of ba3 cytochrome c oxidase from Thermus thermophilus in lipid environment	5/27/2011	T. Tiefenbrunn, W. Liu,Y. Chen, V. Katritch, C.D. Stout, J.A. Fee, V.Cherezov PLoS One.,2011;6:e22348	PDBSum	PubMed
40.	3S8G	1.8 A structure of ba3 cytochrome c oxidase mutant (A120F) from Thermus thermophilus in lipid environment	5/27/2011	T. Tiefenbrunn, W. Liu,Y. Chen, V. Katritch, C.D. Stout, J.A. Fee, V.Cherezov PLoS One.,2011;6:e22348	PDBSum	PubMed
39.	3RZE	Structure of the human histamine H1 receptor in complex with doxepin	5/11/2011	T. Shimamura, M. Shiroishi, S. Weyand, H. Tsujimoto, G. Winter, V. Katritch,R. Abagyan, V. Cherezov, W. Liu, G. W. Han, T. Kobayashi, R. C. Stevens, S. Iwata Nature, 2011;475:65-70.	PDBSum	PubMed
38.	3R1A	Closed crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene	3/09/2011	S.C. Gay, H. Zhang, C.D. Stout, P.F. Hollenberg, J.R. Halpert Biochemistry,2011;50:4903-11	PDBSum	PubMed
37.	3R1B	Open crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene	3/09/2011	S.C. Gay, H. Zhang, C.D. Stout, P.F. Hollenberg, J.R. Halpert Biochemistry, 2011;50:4903-11.	PDBSum	PubMed
36.	1885	Functional Implications of an Intermeshing Cogwheel-Like Interaction between TolC and MacA in the Action of Macrolide-Specific Efflux Pump MacAB-TolC	2/25/2011	Y. Xu, S. Song, A. Moeller, S. Piao, S.-H. Sim, M. Kang, W. Yu, H.-S. Cho, I. Chang, K. Lee, N.-C. Ha J Biol Chem.,2011;286:13541-9.	EMDB	PubMed
35.	3QOA	Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains	2/23/2011	M.B. Shah, J. Pascual, Q.Zhang, C.D. Stout, J.R. Halpert Mol Pharmacol.,2011;80:1047-55.	PDBSum	PubMed
34.	3QU8	Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains	2/09/2011	M.B. Shah, J. Pascual, Q.Zhang, C.D. Stout, J.R. Halpert Mol Pharmacol.,2011;80:1047-55.	PDBSum	PubMed
33.	3QAK	Structure of an agonist-bound human A2A adenosine receptor	1/11/2011	F. Xu, H. Wu, V. Katritch, G. W. Han, K. A. Jacobson, Z. G. Gao, V. Cherezov and R. C. Stevens Science,2011;332:322-7.	PDBSum	PubMed
32.	3POY	Crystal Structure of the alpha-Neurexin-1 ectodomain, LNS 2-6	11/23/2010	M.T. Miller, M. Mileni, D. Comoletti, R.C. Stevens, M. Harel, P. Taylor Structure, 2011;19:767-78	PDBSum	PubMed
31.	3PBL	Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist	10/20/2010	E. Y. Chien, W. Liu, Q. Zhao, V. Katritch, G. W. Han, M. A. Hanson, L. Shi, A. H. Newman, J. A. Javitch, V. Cherezov and R. C. Stevens Science,2010;330:1091-5.	PDBSum	PubMed
30.	3OE6	Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Complex with a small molecule antagonist IT1t in I222 spacegroup	8/12/2010	B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D. J. Hamel, P. Kuhn, T. M. Handel, V. Cherezov and R. C. Stevens Science.,2010;330:1066-71.	PDBSum	PubMed
29.	3ODU	Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Complex with a small molecule antagonist IT1t in P2(1) spacegroup	8/12/2010	B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D. J. Hamel, P. Kuhn, T. M. Handel, V. Cherezov and R. C. Stevens Science,2010;330:1066-71	PDBSum	PubMed
28.	3OE8	Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Complex with a small molecule antagonist IT1t in P1 spacegroup	8/12/2010	B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D. J. Hamel, P. Kuhn, T. M. Handel, V. Cherezov and R. C. Stevens Science,2010;330:1066-71	PDBSum	PubMed
27.	3OE9	Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Complex with a small molecule antagonist IT1t in P1 spacegroup	8/12/2010	B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D. J. Hamel, P. Kuhn, T. M. Handel, V. Cherezov and R. C. Stevens Science,2010;330:1066-71	PDBSum	PubMed
26.	3OE0	Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Complex with a cyclic peptide antagonist CVX15	8/12/2010	B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, D. J. Hamel, P. Kuhn, T. M. Handel, V. Cherezov and R. C. Stevens Science,2010;330:1066-71	PDBSum	PubMed
25.	3NY8	Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography Complex with Inverse Agonist ICI 118,551	7/14/2010	D. Wacker, G. Fenalti, M. A. Brown, V. Katritch, R. Abagyan, V. Cherezov and R. C. Stevens J Am Chem Soc.,2010;132:11443-5.	PDBSum	PubMed
24.	3NY9	Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography Complex with Inverse Agonist Compound 1	7/14/2010	D. Wacker, G. Fenalti, M. A. Brown, V. Katritch, R. Abagyan, V. Cherezov and R. C. Stevens J Am Chem Soc.,2010;132:11443-5.	PDBSum	PubMed
23.	3NYA	Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography Complex with Antagonist Alprenolol	7/14/2010	D. Wacker, G. Fenalti, M. A. Brown, V. Katritch, R. Abagyan, V. Cherezov and R. C. Stevens J Am Chem Soc.,2010;132:11443-5.	PDBSum	PubMed
22.	3MVR	Crystal Structure of cytochrome P450 2B4-H226Y in a closed conformation	5/04/2010	M.B. Shah, C.D. Stout, J.R. Halpert J Biol Chem.,2010;285:38602-11.	PDBSum	PubMed
21.	3MKT	Structure of a Cation-bound Multidrug and Toxin Compound Extrusion (MATE) transporter	4/15/2010	X. He, P. Szewczyk, A. Karyakin, M. Evin, W.-X. Hong, Q. Zhang, G. Chang Nature.,2010;467:991-4.	PDBSum	PubMed
20.	3MKU	Structure of a Cation-bound Multidrug and Toxin Compound Extrusion (MATE) transporter	4/15/2010	X. He, P. Szewczyk, A. Karyakin, M. Evin, W.-X. Hong, Q. Zhang, G. Chang Nature.,2010;467:991-4	PDBSum	PubMed
19.	3ME6	Crystal structure of cytochrome P450 2B4 in complex with the anti-platelet drug clopidogrel	3/31/2010	S.C.Gay, A.G. Roberts, K. Maekawa, J.C. Talakad, W.X. Hong, Q. Zhang, C.D. Stout, J.R. Halpert Biochemistry, 2010;49:8709-20	PDBSum	PubMed
18.	3KW4	Crystal structure of cytochrome P450 2B4 in complex with the anti-platelet drug ticlopidine	11/30/2009	S.C. Gay, K. Maekawa, A.G. Roberts, W. -X. Hong, Q. Zhang, C.D. Stout, J.R. Halpert Biochemistry, 2010;49:8709-20	PDBSum	PubMed
17.	3K9V	Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CHAPS	10/16/2009	A. J. Annalora, D.B. Goodin, W. Hong, Q. Zhang, E. F. Johnson, C.D. Stout J Mol Biol.,2010;396:441-51.	PDBSum	PubMed
16.	3K9Y	Crystal structure of rat mitochondrial P450 24A1 S57D in complex with CYMAL-5	10/16/2009	A. J. Annalora, D.B. Goodin, W. Hong, Q. Zhang, E. F. Johnson, C.D. Stout J Mol Biol.,2010;396:441-51.	PDBSum	PubMed
15.	3IBD	Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole	10/16/2009	S.C.Gay, L. Sun, J.C. Talakad, M.B. Shah, D.C. Stout, J.R. Halpert Mol Pharmacol.,2010;77:529-38.	PDBSum	PubMed
14.	3G61	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding	2/05/2009	Aller, S.G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., Harrell, P.M., Trinh, Y.T., Zhang, Q., Urbatsch, I.L., Chang, G. Science,2009;323:1718-22	PDBSum	PubMed
13.	3G60	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding	2/05/2009	Aller, S.G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., Harrell, P.M., Trinh, Y.T., Zhang, Q., Urbatsch, I.L., Chang, G. Science,2009;323:1718-22	PDBSum	PubMed
12.	3G5U	Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding	2/05/2009	Aller, S.G., Yu, J., Ward, A., Weng, Y., Chittaboina, S., Zhuo, R., Harrell, P.M., Trinh, Y.T., Zhang, Q., Urbatsch, I.L., Chang, G. Science,2009;323:1718-22	PDBSum	PubMed
11.	3EML	The 2.6 A Crystal Structure of a Human A2A Adenosine Receptor bound to ZM241385	9/24/2008	Jaakola, V.-P., Griffith, M.T., Hanson, M.A., Cherezov, V., Chien, E.Y.T., Lane, J.R., Ijzerman, A.P., Stevens, R.C. Science, 2008;322:1211-7	PDBSum	PubMed
10.	3D4S	Cholesterol bound form of human beta2 adrenergic receptor	5/14/2008	Hanson, M.A., Cherezov, V., Roth, C.B., Griffith, M.T., Jaakola, V-P., Chien, E.Y.T., Velasquez, J., Kuhn, P., Stevens, R.C. Structure,2008;16:897-905.	PDBSum	PubMed
9.	3B62	EmrE multidrug transporter in complex with P4P, P21 crystal form	10/26/2007	Chen, Y.J., Pornillos, O., Lieu, S., Ma, C., Chen, A.P., Chang, G. Proc Natl Acad Sci.,2007;104:18999-9004.	PDBSum	PubMed
8.	3B61	EmrE multidrug transporter, apo crystal form	10/26/2007	Chen, Y.J., Pornillos, O., Lieu, S., Ma, C., Chen, A.P., Chang, G. Proc Natl Acad Sci.,2007;104:18999-9004.	PDBSum	PubMed
7.	3B60	Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP, higher resolution form	10/26/2007	Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G. Proc Natl Acad Sci.,2007;104:18999-9004.	PDBSum	PubMed
6.	3B5Z	Crystal Structure of MsbA from Salmonella typhimurium with ADP Vanadate	10/26/2007	Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G. Proc Natl Acad Sci.,2007;104:18999-9004.	PDBSum	PubMed
5.	3B5W	Crystal Structure of Eschericia coli MsbA	10/26/2007	Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G. Proc Natl Acad Sci.,2007;104:18999-9004.	PDBSum	PubMed
4.	3B5Y	Crystal Structure of MsbA from Salmonella typhimurium with AMPPNP	10/26/2007	Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G. Proc Natl Acad Sci.,2007;104:18999-9004.	PDBSum	PubMed
3.	3B5X	Crystal Structure of MsbA from Vibrio cholerae	10/26/2007	Ward, A., Reyes, C.L., Yu, J., Roth, C.B., Chang, G., Proc Natl Acad Sci.,2007;104:18999-9004.:	PDBSum	PubMed
2.	3B5D	EmrE multidrug transporter in complex with TPP, C2 crystal form	10/25/2007	Chen, Y.J., Pornillos, O., Lieu, S., Ma, C., Chen, A.P., Chang, G. Proc Natl Acad Sci., 2007;104:18999-9004.	PDBSum	PubMed
1.	2RH1	High resolution crystal structure of human B2-adrenergic G protein-coupled receptor	10/05/2007	Cherezov, V., Rosenbaum, D.M., Hanson, M.A., Rasmussen, S.G.F., Thian, F.S., Kobilka, T.S., Choi, H.J., Kuhn, P., Weis, W.I., Kobilka, B.K., Stevens, R.C. Science,2007;318:1258-65	PDBSum	PubMed